DY131 is a synthetic selective agonist of estrogen related receptors investigated for its interactions with ERRβ and ERRγ signaling pathways in preclinical models of cellular energy regulation.
Molecular Composition and Mechanistic Profile
Compound identity: DY131 is a small molecule agonist with the molecular formula C18H21N3O2.
Origin: Synthetic compound developed as a pharmacological tool for studying orphan nuclear receptor activity.
Mechanistically, DY131 has been associated with:
Selective activation of estrogen related receptors β and γ in experimental binding and transcriptional assays.
Modulation of downstream pathways involved in energy metabolism and mitochondrial function in laboratory systems.
Influence on gene expression programs regulated by ERRβ and ERRγ in cellular preparations.
These properties position DY131 as a tool for studying selective estrogen related receptor signaling and metabolic regulation.
Integrated Research Applications
DY131 is examined in systems focused on nuclear receptor and energy homeostasis research. Representative domains include:
Estrogen related receptor models: Investigation of selective agonist activity and transcriptional responses in cultured cells.
Metabolic and energy regulation studies: Evaluation of effects on mitochondrial and metabolic pathway markers in experimental systems.
Nuclear receptor comparative research: Assessment of receptor selectivity relative to other ERR modulators in controlled laboratory settings.
Cellular stress and adaptation models: Use as a probe for ERR mediated responses under metabolic challenge conditions.
Analytical Validation, Formulation, and Storage
NextGenPeps supplies DY131 as a high purity research compound. Typical quality and handling features include:
Purity: ≥98% verified by HPLC.
Formulation: Solid material in sealed containers, intended for dissolution with appropriate research grade solvent for experimental use only. No dosing guidance is provided for any organism.
Storage: Keep material in a cool dark dry environment; recommended storage at or near 4 °C. Handle reconstituted solutions according to laboratory defined stability windows.
NextGenPeps supplies DY131 as a high purity research compound intended strictly for controlled laboratory use in vitro or in established animal models, such as murine systems. This compound is not approved as a drug, diagnostic, or dietary ingredient, and is not manufactured, packaged, or marketed for human consumption, self experimentation, clinical application, or any use outside properly designed and ethically approved research protocols.
