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Cardiogen

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Research Use Only: The statements made within this website have not been evaluated by the US Food and Drug Administration. These materials are not intended to diagnose, treat, cure, or prevent any disease. All products are for laboratory research and development use only, and are not intended for human use.

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Product information

Cardiogen is a synthetic tetrapeptide bioregulator investigated for its interactions with cardiac tissue cellular regulation and proliferative signaling in preclinical models.

Molecular Composition and Mechanistic Profile

  • Peptide identity: Cardiogen is a four amino acid peptide with the sequence Ala Glu Asp Arg (AEDR).

  • Origin: Synthetic short regulatory peptide developed from sequences associated with cardiac tissue polypeptides in the bioregulator class.

  • Mechanistically, Cardiogen has been associated with:

    • Stimulation of cell proliferation markers in cardiac tissue preparations from experimental systems.

    • Modulation of fibroblast activity and extracellular matrix related processes in laboratory models.

    • Influence on protein synthesis and cellular regulatory pathways relevant to cardiomyocyte and connective tissue dynamics.

These properties position Cardiogen as a tool for studying tissue specific bioregulatory signaling in cardiac models.

Integrated Research Applications

Cardiogen is examined in systems focused on cardiac and fibroblast regulation. Representative domains include:

  • Cardiomyocyte and cardiac tissue models: Investigation of proliferative responses and metabolic markers in cultured cells and animal tissue preparations.

  • Fibroblast and matrix studies: Evaluation of effects on collagen elastin related synthesis and tissue remodeling signals in experimental systems.

  • Aging related cardiac models: Assessment of cellular activity differences between young and aged tissue preparations.

  • Comparative bioregulator research: Use alongside related short peptides to explore organ specific regulatory mechanisms in controlled laboratory settings.

Overall, Cardiogen serves as a research tool for exploring short peptide modulation of cardiac tissue homeostasis and cellular renewal networks.

Analytical Validation, Formulation, and Storage

NextGenPeps supplies Cardiogen as a high purity research peptide. Typical quality and handling features include:

  • Purity: ≥99% verified by HPLC.

  • Formulation: White lyophilized powder in sealed glass vials, intended for reconstitution with appropriate research grade solvent for experimental use only. No dosing guidance is provided for any organism.

  • Storage: Keep lyophilized material in a cool dark dry environment; long term storage at or below −20 °C. Store reconstituted solutions refrigerated, minimize freeze thaw cycles, and use within laboratory defined stability windows.

These conditions support structural integrity and reproducible experimental outcomes.

NextGenPeps supplies Cardiogen as a high purity research peptide intended strictly for controlled laboratory use in vitro or in established animal models, such as murine systems. This compound is not approved as a drug, diagnostic, or dietary ingredient, and is not manufactured, packaged, or marketed for human consumption, self-experimentation, clinical application, or any use outside properly designed and ethically approved research protocols.

Chemical Properties

Molecular FormulaC₁₈H₃₁N₇O₉
Molecular Weight489.48
Monoisotopic Mass489.2183
Heavy Atom Count34

Common Research Questions

What is Cardiogen?

Cardiogen is a synthetic peptide made of four amino acids, with the most consistently cited sequence being alanine, glutamic acid, aspartic acid, and arginine (Ala-Glu-Asp-Arg, or AEDR). It's part of the Khavinson family of Russian research peptides, and it's specifically assigned to heart tissue.

What does Cardiogen do?

Cardiogen is proposed to work the same way other peptides in this family do, by getting into cells and directly interacting with genetic material rather than acting through a receptor. It's been shown to bind to several histone proteins at specific binding sites, which is thought to open up access to cardiac-specific genes and make them easier for the cell to actually use.

What is a similar peptide to Cardiogen?

The closest comparison is Chelohart, since Chelohart is a broader natural extract taken from animal heart tissue, while Cardiogen is the single, defined synthetic peptide meant to represent one specific active piece of that same tissue, mirroring the extract-versus-purified-fragment relationship seen elsewhere in this peptide family. Vesugen is another frequently paired peptide, since Cardiogen targets the heart muscle itself while Vesugen targets the blood vessels, and the two are often used together for broader cardiovascular coverage.

Frequently Asked Questions

How is Cardiogen packaged?

Cardiogen is supplied in the product format and quantity shown for the selected variant. Please inspect the sealed package when it arrives and contact support promptly if the package or labeling appears damaged.

How is Cardiogen shipped?

Orders are shipped within the United States via USPS. Transit times are typically 3–7 business days, depending on destination and carrier conditions. Tracking information is provided when available.

How should Cardiogen be stored?

Storage requirements are product-specific. Keep Cardiogen in its original labeled container and follow the product documentation or manufacturer instructions supplied with the order. Contact support if the applicable storage guidance is not available.

What is the refund policy for Cardiogen?

Due to the nature of research materials, NextGenPeps orders are final and are not eligible for refunds, returns, or exchanges. Review the shipping and reship policies before ordering.

Is Cardiogen intended for human use?

No. NextGenPeps materials are supplied strictly for laboratory research and development use and are not intended for human or animal consumption, clinical use, diagnostic use, cosmetic use, or dietary use.

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The statements made within this website have not been evaluated by the US Food and Drug Administration. The materials offered by this company are not intended to diagnose, treat, cure, or prevent any disease. All research materials on this site are for laboratory research and development use only, and are not intended for human use.

NextGenPeps is a chemical supplier. NextGenPeps is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act. NextGenPeps is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

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